Prednisone has a more than 60-year history of application in clinical practice and sales in the global market. This glucocorticosteroid was discovered in 1954 by Dr. Arthur Nobile, who worked for the pharmaceutical company Schering-Plow Corporation.
Currently, Prednisone is one of the best-selling glucocorticosteroids, and is widely used in various fields of medicine, including pulmonology, ophthalmology, dermatology and endocrinology.
At the moment, people can buy Prednisone in pharmacies in the form of tablets that contain 1 mg, 5 mg, 20 mg, 25 mg, 50 mg or 2.5 mg of the active substance. In ordinary pharmacies, the medicine is sold only on prescription.
Patients, who do not have a medical prescription, are often wondering, where can I buy over the counter Prednisone? Non-prescription Prednisone is sold in online pharmacies.
Patients buy Prednisone to use it as an anti-inflammatory and immunosuppressive drug. The wide popularity of Prednisone is due to:
- adaptogenic, anti-edematous, anti-inflammatory, antiallergic, antitoxic and other effects;
- marked symptomatic effect that improves the general condition of the patient.
Prednisone also contributes to the formation of a biologically active complex, involved in the synthesis of proteins, including the enzymes that regulate vital processes in cells.
A wide range of physiological and pharmacological effects of Prednisone makes it a cure-all drug for the treatment of bronchial asthma, eczema, dermatitis, conjunctivitis, psoriasis, as well as shock conditions.
Prednisone is a glucocorticosteroid with an average duration of action. The maximum therapeutic effect of Prednisone develops 1-1.5 hours after the ingestion and lasts about 4 hours.
For more information about the action mechanism and therapeutic effects of this glucocorticosteroid, address a pharmacist during the purchase of Prednisone in a pharmacy.
The dosage of Prednisone may be:
- for children: 0.5 mg per kilogram of weight in 3-4 divided doses;
- for adults: the initial daily dose of 20-40 mg with possible increase in dose up to 60-80 mg.
The initial dose and duration of Prednisone administration is selected individually for each patient. The dosage of the glucocorticosteroid depends on:
- severity of disease
- average duration of the disease
- individual drug tolerance
After relief of the main manifestations of the pathological process, the attending physician can recommend switching to intermittent administration of the medication. The essence of the alternate day therapy (ADT) is the introduction of a 48-hour Prednisone dose once every other day, in the morning.
The ADT increases not only the effectiveness, but also the safety of the disease treatment with glucocorticoid therapy.
There are several reasons why Prednisone still remains one of the best-selling glucocorticosteroids, which include its ability to:
- Exert an antitoxic effect
- Suppress the secretion of thyroid-stimulating hormone
- Restore bronchial patency
- Maintain the constancy of the internal environment of the body under unfavorable conditions
Currently, Prednisone is the drug of choice for long-term glucocorticoid therapy. Branded drugs produced on the basis of Prednisone have a single drawback – their high price.
Generic drugs, based on Prednisone, are cheaper, so their purchase allows you to reduce the cost of drug therapy for inflammatory diseases.
The best prices for Prednisone are offered by online pharmacies. In most Internet drugstores, you can buy Prednisone at a discount, and get the required amount of doses of this medicine without leaving your home.
In the USA, Canada and Australia, Prednisone is sold under the trademarks of Rayos, Panafcort, Deltasone and Winpred. In European countries, this drug is known under other brand names. For example, in the UK, Prednisone is sold under the trademark Lodotra, in Sweden – Deltison, in Germany – Cutason and Decortin, and in France – Cortancyl.